0113 206 4927
Summary: I lead the LICAP Clinical and Biomedical Proteomics group.
Location: Cancer Research Building
My research interests are predominantly in biomarker discovery and translation. For more information see the Clinical and Biomedical Proteomics Group website.
Originally graduating in Physiology from St Andrews University in 1982, I have since gained a PhD and had research experience in a variety of areas, initially working for the MRC in Edinburgh but for the last 25 years at the University of Leeds. For the last 21 years I have been based in the Cancer Research UK (formerly ICRF) Centre in Leeds with labs on the St Jamess University hospital campus.
The main focus of our research group is in developing and using proteomics-based approaches in renal cancer, renal transplantation and acute kidney injury, with the aims of discovering novel biomarkers and therapeutic targets and increasing our understanding of the underlying pathogenesis. However with my broad interest in translational medical research, I am also involved in collaborative projects in several other areas.
I also work closely with the clinical teams in the Centre in the translational research aspects of monitoring patients undergoing treatment with biological therapeutics to try and better understand the mechanisms operating in vivo in an attempt to improve patient response and tailoring of therapies. Other activities include responsibility for establishing and overseeing a team dedicated to biobanking with 2 Research Tissue Banks, and provision of internal research and external contract activities in clinical trial sample processing, proteomics and mass spectrometry and assays development/evaluation.
I am a member of the Executive Committee of the British Society for Proteome Research and Senior Associate Editor for the Wiley journals Proteomics Clinical Application and Proteomics.