Dr Dario De Vecchis

Dr Dario De Vecchis

Post-doctoral Research Fellow

+44(0)113 343 8536

Summary: I am a postdoctoral fellow in the group of Dr. Kalli in LICAP. My research involved molecular modelling and large-scale simulations of significant biomolecules mixtures.

Location: Level 5 Wellcome Trust Brenner Building, St James's University Hospital

Overview

Dr De Vecchis obtained a BSc Hons in Bioinformatics from the University of Rome (Italy) where he developed a strong interest in computational methodologies to investigate biological questions. He then moved to Paris (France) in the Institute of Physico-Chemical Biology where he completed his PhD in molecular modelling from the Paris Diderot University under the supervision of Dr Antoine Taly. He is currently a postdoctoral fellow in the research groups of Dr Antreas Kalli at the University of Leeds, Institute of Cancer and Pathology.

His research applies molecular modelling and extensive multi-scale dynamics simulations (i.e. all-atom and coarse-grained) to investigate structure-function relationship that characterise biological macromolecules. In particular, membrane proteins that undergo conformational rearrangements and how lipid environment and cofactors affect their function. His previous research focus on Mitofusins, a class of large GTPases involved in mitochondrial dynamics. He is currently working on red blood cell protein membrane organisation in close link with experimentalists, aiming at characterising the Band 3 anion transporter.