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Summary: Dr Aruna Asipu, Senior Research Fellow, Section of Genetics.
Location: Wellcome Trust Brenner Building
Structural and functional aspects of medically important proteins.
Details: Structural and biochemical aspects by generating recombinant human proteins using E.coli expression system. Functional aspects by generating knock out mouse models. Examples: ketohexokinase, a key enzyme in fructose metabolism; and SAMHD1, a novel regulator in innate immunity.