Dr Caroline Chilton

University Academic Fellow

0113 392 8663

Summary: University Academic Fellow within the HCAI Research Group. Microbiologist with research interests in Clostridium difficile infection (CDI), antibiotic resistance, and the intestinal microbiota.

Location: Microbiology, Old Medical School, Leeds General Infirmary

Teaching Commitments: Lectures


Healthcare Associated Infection (HCAI) poses a huge burden on healthcare facilities worldwide.  Recent years have seen a rise in HCAI caused by multi-drug resistant organisms (MDRO). These hard-to-treat infections massively increase the burden on healthcare systems in terms of prevention, detection, tracking and patient management, which is likely to increase over the next decade.  The bacterial populations of the gut (the intestinal microbiome) are key to HCAI, both in terms of their prevention, but also by harbouring resistant organisms and resistant genes. My research utilises in-vitro modelling of the intestinal microbiome to investigate three main research areas; Clostridium difficile infection (CDI), antibiotic resistance, and the characterisation of microbiome. 

For more details please visit the gut model project page.

2015 - Present  
University Academic Fellow in Infection, Inflammation and Immunity, University of Leeds.

Post Doctoral Research Fellow. Healthcare Associated Infection Research Group, Leeds Institute of Biomedical and Clinical Sciences, University of Leeds.
Supervisor: Professor Mark Wilcox

2007 – 2010   
PhD. Department for Bioanalysis and Horizon Technologies, The Health Protection Agency (now Public Health England), Colindale, London AND The University of Edinburgh.
Thesis: Comparative proteomic analysis of Clostridium difficile
Supervisors: Professors Saheer Gharbia, Haroun Shah, Ian Poxton and SP Borriello