Research in the Section of Experimental Haematology focuses on haematological malignancies and bone marrow failure syndromes. We employ a range of model systems, primary tissue samples and both single cell and omics approaches to analyse the response of cells to novel therapeutic agents, immunological and mutational causes of disease and the events controlling lineage commitment and cell differentiation in the blood and immune system. We are actively involved in the development of novel biomarkers to guide clinical decision making.
We enjoy strong links with the Clinical Haematology Department and Haematological Malignancy Diagnostic Service (http://www.hmds.info/) at Leeds Teaching Hospitals NHS Trust, as well as other partners in the Haematological Malignancy Research Network (http://www.hmrn.org/) of Yorkshire and Humberside.
A principle collaboration with several groups in the Section in relation to the development of systems level and genomic approaches to disease and diagnosis is with the Westhead Lab in the Faculty of Biological Sciences.