Course Content

The course will comprise the following compulsory modules:

Module 1: Fundamentals of Clinical Embryology
Module 2: IVF and Embryo Culture
Module 3: Micromanipulation
Module 4: Cryobiology and Cryopreservation
Module 5: Ethics and Law for Embryologists
Module 6: Research Project Proposal
A detailed breakdown of the Modules is as follows:

Module 1: Fundamentals of Clinical Embryology
Fundamentals of Clinical Embryology
Meiosis
Gametogenesis
Endocrinological control of human reproduction
Molecules of human reproduction
Investigating the male and female patient
Molecular and cellular biology and related techniques eg PCR.
Genetics of infertility.
Reproductive function and causes of subfertility

Module 2: IVF and Embryo Culture
The development of ART
Tissue culture technique
IVF culture media and techniques
Quality control
Health and safety in the laboratory
COSHH.
Handling and culture techniques particular to oocytes and embryos
Oocyte retrieval
Oocyte preparation for ICSI
IVM of oocytes
Follicular culture.
Sperm retrieval methods
Sperm preparation techniques
Preimplantation embryo development
Implantation and placentation.
Miscarriage and ectopic pregnancy
Principles and practices of laboratory design

Module 3: Micromanipulation
Assisted fertilisation and micromanipulation techniques (ICSI, SUZI, Zona Dissection etc.), microtools, assisted hatching.
Embryo biopsy-cleavage stage biopsy, blastocyst biopsy, polar body biopsy, biopsy for PGD + PGD molecular methods.
Embryonic Stem cells, developmental biology, derivation and application
Epigenetics and ART-induced disorders of genomic imprinting

Module 4: Cryobiology and Cryopreservation
Basic cryobiology.
Cryopreservation of gametes, sperm freezing, egg freezing.
Gonadal cryopreservation.
Embryo cryopreservation.

Module 5: Ethics and Law for Embryologists
Ethics and clinical embryology.
Ethical issues and problems in clinical embryology.

Module 6 (Masters level)
Design and develop a research project proposal in assisted reproduction technology