Globally, chronic disease prevalence is high and rising as a result of changing tobacco use, diets and activity levels. Most chronic disease can be prevented or controlled by self-management of these risk factors. While there is some evidence supporting the use of health behaviour change interventions, there is scope to develop more effective interventions, as well as developing the underpinning evidence and theoretical frameworks on which these are based. Most work has focused on applying such interventions within higher income countries (HICs); the need to develop robust behaviour change interventions suitable for delivery in lower income countries (LICs) is particularly acute. Bringing together expertise across the University of Leeds, we are expanding our work in the development of theory-based health behaviour change interventions in HICs and in LICs. In undertaking our research we collaborate extensively with established research teams in Psychology, Clinical Trials and Applied Health Research.